Sleep, Circadian Rhythms, and Parkinson’s Disease

Research over the past decade has shown that disturbances of sleep and daily biological rhythms are not peripheral symptoms of Parkinson’s disease, but integral features of the condition. Changes in circadian timing systems, sleep architecture, and daily physiological rhythms interact with established Parkinson’s pathology to shape symptoms, fluctuations, and quality of life. Understanding these processes helps explain fatigue, poor sleep, and day–night instability, and highlights why sleep deserves focused attention in Parkinson’s care.

Source: Sleep and circadian rhythms in Parkinson’s disease and preclinical models